2016

359. Zhang, A. H.;Liu, W.;Jiang, N.;Xu, Q.;Tan, R.X. Spirodalesol, an NLRP3 Inflammasome Activation Inhibitor. Org. Lett., 2016, 18 (24), 6496–6499.

358. Zhang, A. H.; Tan, R.;Jiang, N.;Kaidiriye, Y.;Wang, G.;Wang, X.L.;Tan, R.X. Selesconol, a Fungal Polyketide That Induces Stem Cell Differentiation. Org. Lett., 2016, 18 (21), 5488–5491.

357. Han, W. B.; Zhang, A. H.; Deng, X. Z.; Lei, X.; Tan, R. X. Curindolizine, an Anti-inflammatory Agent Assembled via Michael Addition of Pyrrole Alkaloids inside Fungal Cells. Org. Lett. 2016, 18, 1816−1819.

356. Zong,  W.; Li, G. W.; Cao, J. M.; Lei, X. X.*; Hu, M. L.; Sun, H.*;  Griesinger, C.; Tan, R. X.*  An alignment medium for measuring residual  dipolar couplings in pure DMSO: liquid crystals from graphene oxide  grafted with polymer brushes. Angew. Chem. Int. Ed. 2016, 55, doi.org/10.1002/anie.201511435.

355. Li,  G. W.; Cao, J. M.; Zong, W.; Lei, X. X.*; Tan, R. X.*  Enantiodiscrimination of carboxylic acids using the diphenylprolinol NMR  chiral solvating agents. Org. Chem. Front. 2016, 3, 96–102.


2015

354. Zhao,  Z. B.; Wang, L.; James, T.; Jung, Y.; I. Kim, I.; Tan, R. X.; Hoffmann,  F. M.; Xu, W.* Reciprocal regulation of ERα and ERβ stability and  activity by diptoindonesin G. Chem. Biol. 2015, 22, 1608–1621.

353. Jia,  J. J.; Fan, H. Y.; Li, F. L.; Li, X. J.; Dong, G. J.; Gong, W.; Song,  Y. X.; Liu, F.; Hua, C. Y.; Tan, R. X.; Dou, H.*; Hou, Y. Y.* A  benzenediamine derivative fc-99 attenuates lupus-like syndrome inMRL/lpr  mice related to suppression of pDC activation. Immunol. Lett. 2015, 168, 355–365.

352. Song,  Y. N.; Zhang, W. J.;  Bi, S. F.; Jiao, R. H.; Tan; R. X.*; Ge, H. M.*  New ansamycin analogues from the mutant strain of Streptomyces  seoulensis. J. Antibiot. 2015, 68, 757-759.

351. Chen,  C. J.; Zhou, Y. Q.; Liu, X. X.; Zhang, W. J.; Hu, S. S.; Lin, L. P.;  Huo, G. M.; Jiao, R. H.; Tan; R. X.*; Ge, H. M.* Antimicrobial and  anti-inflammatory compounds from a marine fungus Pleosporales sp. Tetrahedron Lett. 2015, 56, 6183–6189.

350. Guo, Z. K.; Yan, W.; Tan, R. X.; Ge, H. M.* Actinotetraose L, a new tetrasaccharide derivative isolated from the mycelia of Amycolatopsis sp. HCa1. J. Asian Nat. Prod. Res. 2015, 17, 1109-1113.

349. Kong, L. Y.; Tan, R. X.* Artemisinin, a miracle of traditional Chinese medicine. Nat. Prod. Rep. 2015, 32, 1617–1621.

348. Guo,  X. C.; Liu, T. X.; Shi, H. F.; Wang, J. J.; Ji, P.; Wang, H. W.; Hou,Y.  Y.; Tan, R. X.; Li, E. G.* Respiratory syncytial virus infection  upregulates NLRC5 and major histocompatibility complex class I  expression through RIG-I induction in airway epithelial cells. J. Virol. 2015, 89, 7636–7645.

347. Zhou,  L.; Song, F. M.; Liu, Q.; Yang, M. L.; Zhao, J. M.; Tan, R. X.; Xu, J.;  Zhang, G.; Quinn, J. M. W.; Tickner, J.; Xu, J. K.* Berberine sulfate  attenuates osteoclast differentiation through RANKL induced NF-B and  NFAT pathways. Int. J. Mol. Sci. 2015, 16, 27087–27096.

346. Chen,  C. M.; Zhang, W.; Shi, H. F.; Zhuo, Y. J.; Yang, G.; Zhang, A. H.; Hou,  Y. Y.; Tan, R. X.; Li, E. G.*  A novel benzenediamine derivative FC98  reduces insulin resistance in high fat diet-induced obese mice by  suppression of metaflammation. Eur. J. Pharmacol. 2015, 15, 298–308.

345. Wang,  G.; Fan, J. Y.; Zhang,W. J.; Hua, C. P.; Chen, C. J.; Yan, W.; Ge, H.  M.; Jiao, R. H.*; Tan, R. X. Polyketides from mantis-associated fungus Daldinia eschscholzii IFB-TL01. Chem. Biodivers. 2015, 12, 1349–1355.

344. Ren, R.; Chen, C. J.; Liu, X. X; Ge, H. M.; Tan, R. X.*; Jiao, R. H.* Bioactive trichothecenes produced by the Myrothecium sp. QB-1. Helv. Chim. Acta. 2015, 98, 1435–1441.

343. Qin,  S. N.; Ang, E.; Dai, L. B.; Yang, X. H.; Ye, D. P.; Chen, H. H.; Zhou,  L.; Yang, M.; Teguh, L. D.; Tan, R. X.; Xu, J.; Tickner, J.; Pavlos, N.  J.*; Xu, J. K.* Natural germacrane sesquiterpenes inhibit osteoclast  formation, bone resorption, RANKL-induced NF-B activation, and IBα  degradation.  Int. J. Mol. Sci. 2015, 16, 26599–26607.

342. Liu,  M.; Huang, F.; Zhang,  F. D.; Ju, J. Y.; Wu, X. B.; Wang, Y. Y.; Wang,  D.; Wu, Y. P.; Nie, M.; Li, Z.; Ma, C. C.; Chen, X.; Zhou, J. Y.; Tan,  R. X.; Yang, B. L.; Zen, K.; Zhang, C. Y.; Chen, Y. G.*; Zhao, Q.*  Heterochromatin protein HP1g promotes colorectal cancer progression and  is regulated by miR-30a. Cancer Res. 2015, 75, 1–12.

341. Ju,  J.; Wang, Y. Y.; Liu, R. H.; Zhang, Y. C.; Xu, Z.; Wang, Y. D.; Wu, Y.  P.; Liu, M.; Cerruti, L.; Zou, F.; Ma, W.; Fang, C. M.; Tan, R. X.;  Jane, S. M.*; Zhao, Q.* Human fetal globin gene expression is regulated  by LYAR. Nucleic Acids Res. 2015, 42, 9740–9752.

340. Pan,  Z. H.; Jiao, R. H.; Lu, Y. H.*; Tan, .R. X. Enhancement of dalesconols A  and B production via upregulation of laccase activity by medium  optimization and inducer supplementation in submerged fermentation of  Daldinia eschscholzii.Bioresource Technol. 2015, 192, 346–353.

339. Zhang, W. J.; Wei, W.; Shi, J.; Chen, C. J.; Zhao, G. Y.; Jiao, R. H.*; Tan, R. X. Natural phenolic metabolites from endophytic Aspergillus sp. IFB-YXS with antimicrobial activity. Bioorg. Med. Chem. Lett. 2015, 25, 2698–2701.

338. Hu,  S. S.; Jiang, N.; Wang, X. L.; Chen, C. J.; Fan, J. Y.; Wurin, G. G.;  Ge, H. M.; Tan, R. X.; Jiao, R. H.* Prenylated diphenyl ethers from the  mantis-associated fungus Aspergillus versicolor GH-2. Tetrahedron Lett. 2015, 56, 3894–3897.

337. Zhang, X.; Wei, W.; Tan, R. X.* Symbionts, a promising source of bioactive natural products. Sci. China Chem. 2015, 58, 1097–1109.

336. Lin,  L. P.; Yuan, P.; Jiang, N.; Mei, Y. N.; Zhang, W. J.; Wu, H. M.; Zhang,  A. H,; Cao, J. M.; Xiong, Z. X.; Lu, Y.; Tan, R. X.* ene-inspired  mycosynthesis of skeletally new indole alkaloids. Org. Lett. 2015, 17, 2610–2613.

335. Liu,  Q.; Zhao, J.; Tan, R. X.; Zhou, H.; Lin, Z.; Zheng, M.; Romas, E.; Xu,  J.; Sims, N. A. Parthenolide inhibits pro-inflammatory cytokine  production and exhibits protective effects on progression of  collagen-induced arthritis in a rat model. Scand. J. Rheumatol. 2015, 44, 182–191.

334. Tian  Y.; Zhao, G. Y.; Fang, W.; Xu, Q.; Tan, R. X.* 10(E)-sphingolipid  desaturase involved in fusaruside mycosynthesis and stress adaptation in  Fusarium graminearum. Sci. Rep. 2015, 5, 10486.

333. Ren,  R.; Chao, J. C.; Hu, S. S.; Hui, M. Ge.; Zhu, W. Y.; Tan , R. X.*,  Jiao, R. H.* Drimane Sesquiterpenoids from the Aspergillus oryzae  QXPC-4. Chem. Biodiv. 2015, 12, 371–379.

332. Yao,  L.Y.; Zhu, Y. X.; Liu, C. Q.; Jiao, R. H.; Lu, Y. H.*; Tan, R. X.*  Preparative separation and purification of fumigaclavine C fromfermented  mycelia of Aspergillus fumigatus CY018 by macroporousadsorption resin. J. Chromatogr. B 2015, 989, 122–128.

331. Tian,  Y.; Jiang, N.; Zhang, A. H.; Chen, C. J.; Deng, X. Z.; Zhang, W. J.;  Tan, R. X.* Muta-mycosynthesis of naphthalene analogs. Org. Lett. 2015, 17, 1457–1460.

330. Song,  Y. N.; Jiao, R. H.; Zhang, W. J.; Zhao, G. Y.; Dou, H.; Jiang, R.;  Zhang, A. H.; Hou, Y. Y.; Bi, S. F.; Ge, H. M.*; Tan, R. X.* New  ansamycin derivatives generated by simultaneous mutasynthesis. Org. Lett. 2015, 17, 556–559.

329. Han,  W. B.; Dou, H.; Yuan, W. H.; Gong, W.; Hou, Y. Y.*; Ng, S. W.; Tan, R.  X.* Meroterpenes with Toll-like receptor 3 regulating activity from the  endophytic fungus Guignardia mangiferae. Planta Med. 2015, 81, 145–151.

328. Chen,  C. J.; Liu, X. X.; Zhang, W. J.; Zang, L. Y.; Wang, G.; Ng, S. W.; Tan,  R. X.*; Ge, H. M.* Sesquiterpenoids isolated from an endophyte fungus Diaporthe sp. RSC Adv. 2015, 5, 17559–17565.

327. Zhao,  G. Y.; Fan,  J. Y.; Hua, C. P.; Yan, W.; Chen, C. J.; Lu, Y. H.; Jiao,  R. H.*; Tan, R. X.* Resveratrol improves fungal ribosylation capacity  through a unique mechanism. RSC Adv. 2015, 5, 5657–5663.

326. Huang,  J. B.; Zhou, L.; Wu, H. F.; Pavlos, N.; Chim, S. M.; Liu, Q.; Zhao, J.  M.; Xue, W.; Tan, R. X.; Ye, J. M.; Xu, J.; Ang, E. S. M.; Feng,  H.;  Tickner,T. J. Xu, J. K.*; Ding ,Y.* Triptolide inhibits osteoclast  formation, bone resorption, RANKL-mediated NF-қB activation and titanium  particle-induced osteolysis in a mouse model. Mol. Cell. Endocrinol. 2015, 399, 346–353.

325. Wang,  J. J.; Guo, X. C.; Yang, Z. Y.; Tan, R. X.; Chen, X. Q.*; Li, E. G.*  Fungal metabolite myriocin promotes human herpes simplex virus-2  infection. Life Sci. 2015, 120, 31–38.


2014

324. Yan,  W.; Ge, H. M.; Wang, G.; Jiang, N.; Mei,Y. N.; Jiang, R.; Li, S. J.;  Chen, C. J.; Jiao, R. H.; Xu, Q.; Ng, S. W.; Tan, R. X.* Pictet–Spengler  reaction based biosynthetic machinery in fungi. Proc. Natl.Acad. Sci. USA 2014, 111, 18138–18143.

323. Guo,  Z. K.; Wang, R,; Huang, W.; Li, X. N.; Jiang, R. Tan, R. X.*; Ge, H.  M.* Aspergiloid I, an unprecedented spirolactone norditerpenoid from the  plant-derived endophytic fungus Aspergillus sp. YXf3. Beilstein J. Org. Chem. 2014, 10, 2677–2682.

322. Wang,  X.; Zhang, A.; Gao, J.; Chen,W.; Wang, S.; Wu, X.; Shen, Y.; Ke, Y.;  Hua, Z.; Tan, R. X.*; Sun, Y.*; Xu, X.* Trichomide A, a natural  cyclodepsipeptide, exerts immunosuppressive activity against activated  T-lymphocytes by upregulating shp2 activation to overcome contact  dermatitis. J. Invest. Dermatol. 2014, 134, 2737–2746.

321. Shen,  L. Luo, Q.; Shen, Z. P.; Li, L. Y.; Zhang, X. J.; Wei, Z. Q.; Fu, Y.;  Song, Y. C.; Tan, R. X.* . A new cytochalasin from endophytic Phomopsis  sp. IFB-E060. Chin. J. Nat. Med. 2014, 12, 512–516.

320. Gong,  W.; Lu, E. L.; Dou, H.; Song, Y. X.;Yang, L.;Ji, J. J.; Li, E. G.; Tan,  R. X.* Hou, Y. Y.* A novel 1,2-benzenediamine derivative FC-99  suppresses TLR3 expression and ameliorates disease symptoms in a mouse  model of sepsis. Br. J. Pharmacol. 2014, 171, 1577–1579.

319. Ji,  J.J.; Dou, H. X.; Li, Q.; Song, Y. X.; Li, X. J.; Li, E. G.; Tan, R.  X.; Hou, Y. Y. * Novel benzenediamine derivative FC99 ameliorates  zymosan-induced arthritis by inhibiting RORgt expression and Th17 cell  differentiation. Acta Biochim. Biophys. Sin. 2014, 46, 829–836.

318. Han,  W. B.; Lu, Y. H.; Zhang, A. H.; Zhang, G. F.; Mei, Y. N.; Jiang, N.;  Lei, X. X. Song, Y. C.; Tan, R. X.* Curvulamine, a new antibacterial  alkaloid incorporating two undescribed units from a Curvularia species. Org. Lett. 2014, 16, 5366–5369.

317. Chen,  C. J.; Jiang, R.; Wang, G.; Jiao, R. H.; Tancharoen, C.; Sudto,K.;  Vajarothi, S.; Hannongbua, S.; Ge, H. M.*; Tan, R. X.* Oligostibenoids  with acetylcholinesterase inhibitory activity from Dipterocarpus alatus. Planta Med. 2014, 80, 1641–1646.

316. Zhang,  W.; Qiao, H. S.; Lv, Y. Z.; Wang, J. J.; Chen, X. Q.; Hou, Y. Y.; Tan,  R. X.*; Li, E. G.* pigenin Inhibits Enterovirus-71 Infection by  disrupting viral RNA association with trans-acting factors. PLoS ONE 2014, 9, e110429.

315. Huang,  W.; Zhang, W. J.; Cheng, Y. Q.; Jiang, R.; Wei, W.; Chen, C. J.; Wang,  G.; Jiao, R. H.; Tan, R. X. *; Ge, H. M. * Cytotoxic and antimicrobial  flavonoids from Cryptocarya concinna. Planta Med. 2014, 80, 925–930.

314. Zhu,  X. L.; Wang, S. L.; Yu, L. J.; Yang, H.; Tan, R. X.; Yin, K. L.; Jin,  J.;  Zhao, L.H.; Guan, D. N.; Xu,Y. TL-2 attenuates β-amyloid induced  neuronal apoptosis through the AKT/GSK-3β/β-catenin pathway. Int. J. Neuropsychoph. 2014, 17, 1511–1519.

313. Wei, W.; Gao, J.; Shen, Y.; Chu, Y. L.; Xu, Q.*; Tan, R. X. * Immunosuppressive diterpenes from Phomopsis sp. S12. Eur. J. Org. Chem. 2014, 5728–5734.

312. Xu,  J.; Song, Y. C.*; Guo, Y.; Mei, Y. N.; Tan, R. X. * Fumigaclavines D–H,  new ergot alkaloids from endophytic Aspergillus fumigatus. Planta Med. 2014, 80, 1131–1137.

311. Wu,  Q.; Jiang,N.; Han, W. B.; Mei,Y. N.; Ge, H. M.; Guo, Z. K.; Weng, N.  S.; Tan, R. X.* Antibacterial epipolythiodioxopiperazine and  unprecedented sesquiterpene from Pseudallescheria boydii, a beetle  (coleoptera)-associated fungus Org. Biomol. Chem. 2014, 12, 9405–9412.

310. Lei,  X. X.;* Xu, Z.; Sun, H.; Wang, S.; Christian Griesinger, Peng, L.; Gao,  C.*; Tan, R. X.* Graphene oxide liquid crystals as a versatile and  tunable alignment medium for the measurement of residual dipolar  couplings in organic solvents. J. Am. Chem. Soc. 2014, 136, 11280–11283.

309. Wu,  H. C.; Ge, H. M.; Zang, L. Y.; Bei, Y. C.; Niu, Z. Y.; Wei, W. ; Feng,  X. J.; Ding, S.; N, S. W.; Shen, P. P.;* Tan, R. X.* Diaporine, a novel  endophyte-derived regulator of macrophage differentiation. Org. Biomol. Chem. 2014, 12, 6545–6548

308. Zhu,  Y. X.; Yao, L. Y.; Jiao, R. H.; Lu, Y. H.;* Tan, R. X.* Enhanced  production of fumigaclavine C in liquid culture of Aspergillus fumigatus  under a two-stage process. Bioresource Technol. 2014, 152, 162–168。

307. Yao,  L. Y.; Zhu, Y, X.; Jiao, R. H.; Lu, Y. H.;*; Tan, R. X.* Enhanced  production of fumigaclavine C by ultrasound stimulation in a two-stage  culture of Aspergillus fumigatus CY018. Bioresource Technol. 2014, 159, 112–117.

306. Du,  R. H.; Qin, S. Y.; Shi, L. S.; Zhou, Z. Q.; Zhou, X. Y.; Liu, J.; Tan,  R. X. , Cao, W. S.* Fumigaclavine C activates PPARγ pathway and  attenuates atherogenesis in ApoE-deficient mice. Atherosclerosis. 2014, 234, 120-128

305. Wei, W.; Jiang, N.; Mei, Y. N.; Chu, Y. L.; Ge, H. M.; Song, Y. C.; N, S. W.; Tan, R. X.* An antibacterial metabolite from Lasiodiplodia pseudotheobromae F2. Phytochemistry. 2014, 100, 103-109.

304. Yang,  Y. H.; Dou, H.; Li, X. Q.; Song, Y. X.; Gong, W.; Tan, R. X.; Hou, Y.  Y.* FC-98 Regulates TLR9-Mediated of CXCL-10 Expression in Dendritic  Cells via MAPK and STAT1 Signaling Pathway. BioMed Res Int. 2014, 926130.


2013

303. Li,  S. F.; Huang, X. F.; Zhang, D. P.; Huang, Q. L.; Pei, G. S.; Wang, L.  X.;  Jiang, W. H.; Hu, Q. G.; Tan, R. X.; Hua, Z. C.* Requirement of  PEA3 for Transcriptional Activation of FAK Gene in Tumor Metastasis. PLOS ONE 2013, 8, e79336.

302. Qiao,  H. S.; Chen, X. Q.; Xu, L. F.; Wang, J. J.; Zhao, G. Y.; Hou, Y. Y.;  Ge, H. M.; Tan, R. X.* ; Li, E. G.* Antitumor effects of naturally  occurring oligomeric resveratrol derivatives. FASEB J. 2013, 27, 4561–4571.

301. Liu,  Q.; Wu, H. F.; S. M. Chim; Zhou, L.; Zhao, J. M.; Feng, H. T.; Wei, Q.  L.; Wang, Q.; Zheng, M. H.; Tan, R. X.; Gu, Q.; Xu, J.; N. Pavlos; J.  Tickner;Xu, J. K.* SC-514,  a  selective  inhibitor  of  IKKβ   attenuates  RANKL-induced osteoclastogenesis  and  NF-κB  activation.  Biochem. Pharmacol. 2013, 86, 1775–1783.

300. Zhang,  A. H.; Wang, X. Q.; Han, W. B.; Sun, Y.; Guo, Y.; Wu, Q.; Ge, H. M.;  Song, Y. C.; Ng, S. W.; Xu, Q.;* Tan, R. X.* Discovery of a New Class of  Immunosuppressants from Trichothecium roseum Co-inspired by Cross-Kingdom Similarity in Innate Immunity and Pharmacophore Motif. Chem. Asian J. 2013, 8, 3101–3107.

299. Wurin,  G. G.; Guo, Z. K.; Wei, W.; Jiao, R. H.; Yan, T.; Zang, L. Y.; Jiang,  R.; Tan, R. X.*, Ge, H. M.* Polyketides from the plant endophytic fungus  Cladosporium sp. IFB3lp-2. J. Asian. Nat. Prod. Res. 2013, 15, 928–933.

298. Liu,  W.; Guo, W. J.; Wu, J.; Luo, Q.; Tao, F. F.; Gu, Y. H.; Shen, Y.; Li,  J. X.; Tan, R. X.; Xu, Q.;* Sun, Y.* A novel benzo[d]imidazole derivate  prevents the development of dextran sulfate sodium-induced murine  experimental colitis via inhibition of NLRP3 inflammasome. Biochem. Pharmacol. 2013, 85, 1504–1512.

297. Feng, R.; Wang, T.; Wei, W.; Tan, R. X.; Ge, H. M.* Cytotoxic constitutents from Cryptocarya maclurei.Phytochemistry 2013, 90, 147–153.

296. Han,  L. J.; Yin, K. L.; Zhang, S. Y.; Wu, Z. Z.; Wang, C. L.; Zhang, Q. S.;  Pan,  J.; Chen, B. L.; Li, J.; Tan, R. X.; Xu, Y.* Dalesconol B inhibits  lipopolysaccharide induced inflammation and suppresses NF-kappa B and  p38/JNK activation in microglial cells. Neurochem. Int. 2013, 62, 913–921.

295. Hua,  C. Y.; Sun, L.; Yang, Y. H.; Tan, R. X.; Hou, Y. Y.* Mechanisms of  CpG-induced CD40 expression on murine bone marrow-derived dendritic  cells.  Autoimmunity 2013, 46, 177–187.

294. Song, Y.  X.; Dou, H.; Gong, W.; Liu, X. Q.; Yu, Z. G.; Li, E. G.; Tan, R. X.*;  Hou, Y. Y.* Bis-N-norgliovictin, a small-molecule compound from marine  fungus, inhibits LPS-induced inflammation in macrophages and improves  survival in sepsis  Eur. J. Pharmacol. 2013, 705, 49–60.

293. Bi, S. F.; Guo, Z. K.; Jiang, N.; Jiao, R. H.; Ge, H. M.; Tan, R. X.* New alkaloid from Streptomyces koyangensis residing in Odontotermes formosanus. J. Asian. Nat. Prod. Res. 2013, 15, 422–425.

292. Yan,  T.; Guo, Z. K.; Jiang, R.; Wei, W.; Wang, T.; Guo, Y.; Song, Y. C.;  Jiao,  R. H.; Tan, R. X.; Ge, H. M.* New flavonol and diterpenoids from  the endophytic fungus Aspergillus sp. YXf3. Planta Med. 2013, 79, 348–352.

291. Jiao,  R. H.; Xu, H.; Cui, J. T.; Ge, H. M.; Tan, R. X.* Neuraminidase  Inhibitors from marine-derived actinomycete Streptomyces seoulensis. J. Appl. Microbiol. 2013, 114, 1046–1053.

290. Feng,  L. L.; Wu, X. F.; Liu, H. L.; Guo, W. J.; Luo, Q.; Tao, F. F.; Ge, H.  M.; Shen, Y.; Tan, R. X.*; Xu, Q.*; Sun,Y.* Vaticaffinol, a resveratrol  tetramer, exerts more preferable immunosuppressive activity than its  precursor in vitro and in vivo through multiple aspects against  activated T lymphocytes. Toxicol. Appl. Pharm. 2013, 267, 167–173.

289. Chen,  X. Q.; Wang, C. Y.; Xu, L. F.; Chen, X. S.; Wang, W.; Yang, G.; Tan, R.  X.; Li, E. G.; Jin, Y. A laboratory evaluation of medicinal herbs used  in China for the treatment of hand, foot, and mouth disease. Evid.-Based  Compl. Alt. 2013, Article ID 504563. Evid.-Based Compl. Alt. 2013, Article ID 504563.

288. He,  Y. H.; Rank, G.; Zhang, M. M.; Ju, J. Y.; Liu, R. H.; Xu, Z.; F. Brown;  L. Cerruti; Ma, C.; Tan, R. X.; Jane, S. M.*; Zhao, Q.* Induction of  human fetal hemoglobin expression by adenosine-2’,3’-dialdehyde. J. Transl. Med. 2013, 11, 14.

287. Wang,  J. M.; Jiang, N.; Ma, J.; Yu, S. S.; Tan, R. X.; Dai, J. G.; Si, Y. K.;  Ding, G. Z.; Ma, S. G.; Qu, J.; Fang, L.; Du, D. Study on absolute  configurations of alpha/alpha ' chiral carbons of thiodiketopiperazines  by experimental and calculated circular dichroism spectra. Tetrahedron 2013, 69, 1195–1201.

286. Guo,  Z. K.; Jiao, R. H.; Dai, H. F.; Mei, W. L.; Tan,R. X.; ∗ Ge, H. M. ∗  Actinotetraoses I-K, tetrasaccharide metabolites produced by an  insect-der actinobacterium Amycolatopsis sp. HCa1. Chem. Biodivers. 2013, 10, 296–302.

285. Wu, Q.; Guo, Y.; Guo, Z. K.; Chu, Y. L.; Wang, T.; Tan, R. X.* Two new cytosporones from the culture of endophytic Phomopsis sp. Chem. Nat. Compd. 2013, 48, 938-941.

284. Zhu,  X. L.; Ye, L.; Ge, H. M.; Chen, L.; Jiang, N.; Qian, L.; Li, L. L.;  Liu, R.; Ji, S.; Zhang, S.; Jin, J. L.; Guan, D. N.; Fang, W.; Tan, R.  X.;* Xu, Y.* Hopeahainol A attenuates memory deficits by targeting  -amyloid in APP/PS1 transgenic mice. Aging Cell 2013, 12, 85–92.

283. Hua,  C. Y.; Yang, Y. H.; Sun, L.; Dou, H.; Tan, R. X.;* Hou, Y. Y.*  Chaetoglobosin F, a small molecule compound, possesses immunomodulatory  properties on bone marrow-derived dendritic cells via TLR9 signaling  pathway. Immunobiology, 2013, 218, 292–302.


2012

282. Lin,  L.; Ge, H. M.; Yan, T.; Qin, Y. H.; Tan, R. X. * Thaxtomin A-deficient  endophytic Streptomyces sp. enhances plant disease resistance to  pathogenic Streptomyces scabies. Planta, 2012, 236, 1849–1861.

281. Wu,  X. X.; Guo, W. J.; Wu, L. M.; Gu, Y. H.; Gu, L. Y.; Xu, S. H.; Wu, X.  F.; Shen, Y.; Ke, Y. H.; Tan, R. X.; * Sun,Y.;∗ Xu,Q. * Selective  sequestration of STAT1 in the cytoplasm via phosphorylated SHP-2  ameliorates murine experimental colitis. J. Immunol. 2012, 189, 3497–3507.

280. Guo,  Z. K.; Liu, S. B.; Jiao, R. H.; Wang, T.; Tan, R. X.; * Ge, H. M. *  Angucyclines from an insect-derived actinobacterium Amycolatopsis sp.  HCa1 and their cytotoxic activity. Bioorg. Med. Chem. Lett. 2012, 22, 7490–7493.

279. Wu,  X. X.; Sun,Y.; * Guo, W. J.; Gu, Y. H.; Wu, X. F.; Tan, R. X.; Xu,Q. * Rebuilding the balance of STAT1 and STAT3 signalings by fusaruside, a  cerebroside compound, for the treatment of T-cell-mediated fulminant  hepatitis in mice. Biochem. Pharmacol. 2012, 84, 1164–1173.

278. Wu,  X. F.; Wu, X. X.; Guo, W. J.; Luo, Q.; Gu, Y. H.; Shen, Y.; Tan, R. X.;  Sun,Y.;* Xu,Q. * Cerebroside D, a glycoceramide compound, improves  experimental colitis in mice with multiple targets against activated T lymphocytes. Toxicol. Appl. Pharm. 2012, 263, 296–302.

277. Fang,  W.; Ji, S.; Jiang, N.; Wang, W.;  Zhao, G. Y.; Zhang, S.; Ge, H. M.;  Xu, Q. ; Zhang, A. H.; Zhang, Y. L.; Song, Y. C.; Zhang, J.; Tan, R. X.*  Naphthol radical couplings determine structural features and  enantiomeric excess of dalesconols in Daldinia eschscholzii. Nat. Commun. 2012, 3: 1039 doi:10.1038/ncomms2031.

276. Xu,  H. W.; Wei, Y. N.; Zhang, Y.;  Xu, Y. C.; Li, F.; Liu, J.; Zhang, W.;  Han, X. D.; Tan, R. X.; Shen, P. P.* Oestrogen attenuates tumour  progression in hepatocellular carcinoma. J. Pathol. 2012, 228, 216–229.

275. Ge, H. M.; Zhang, L. D.; Tan, R. X.; Yao, Z. J.* Protecting group-free total synthesis of (−)-lannotinidine B. J. Am. Chem. Soc. 2012, 134, 12323−12325.

274. Chen,  X. Q.; Qiao, H. S.; Liu, T. X.; Yang, Z. Y.; Xu, L. F.; Xu, Y. X.; Ge,  H. M.;  Tan, R. X.;* Li, E. G.* nhibition of herpes simplex virus  infection by oligomeric stilbenoids through ROS generation. Antivir. Res. 2012, 95, 30–36.

273. Zang, L. Y.; Wei, W.; Wang, T.; Guo, Y.; Tan, R. X.;* Ge, H. M.∗ sochromophilones from an endophytic fungus Diaporthe sp. Nat. Prod. Bioprospect. 2012, 2, 117–120.

272. Zang,  L. Y.; Wei, W.; Guo, Y.; Wang, T.; Jiao, R. H.; Ng, S. W.; Tan, R. X.;  Ge, H. M.* Sesquiterpenoids from the mangrove-derived endophytic fungus Diaporthe sp.  J. Nat. Prod. 2012, 75, 1744−1749.

271. Sun,  L.; Hua, C. Y.; Yang, Y. H.; Dou, H.; Li, E. G.; Tan,R. X.;* Hou*,Y.  Y. Chaeoglobosin Fex inhibits poly(I:C)-induced activation of bone  marrow-derived dendritic cells. Mol. Immunol. 2012, 51, 150–158.

270. Ge,  H. M.; Sun, H.; Jiang, N.; Qin, Y. H.; Dou, H.; Yan, T.; Hou, Y. Y.;  Griesinger, C.*; Tan, R. X.* Relative and absolute configuration of  vatiparol (1 mg): a novel antiinflammatory polyphenol. Chem. Eur. J. 2012, 18, 5213–5221.

269. Guo,  Z. K.; Yan, T.; Guo, Y.; Song, Y. C.; Jiao, R. H.; Tan, R. X.; Ge, H.  M. * p-Terphenyl and diterpenoid metabolites from endophytic Aspergillus sp. YXf3. J. Nat. Prod. 2012, 75, 15−21.

268. Feng, R.; Guo, Z. K.; Yan, C. M.; Li, E. G.; Tan, R. X.; Ge, H. M. * Anti-inflammatory flavonoids from Cryptocarya chingii. Phytochemistry 2012, 76, 98–105.

267. Zhang,  G. F.; Han, W. B.; Cui, J. T.; Ng, S. W.; Guo, Z. K.; Tan, R. X.; Ge,  H. M. ∗ Neuraminidase inhibitory polyketides from the marine-derived  fungus Phoma herbarum. Planta Med. 2012, 78, 76–78.

266. u,  R. H.; Cui, J. T.; Wang, T.; Zhang. A. H.; Tan, R. X. * Trichothecin  induces apoptosis of HepG2 cells via caspase-9 mediated activation of  the mitochondrial death pathway. Toxicon 2012, 59, 143–150.


2011

265. Zhou,  T.; Song, Y. C.;* Feng, M. Q.; Tan, R. X.* Cloning, expression and  biochemical characterization of UDP-glucose 6-dehydrogenase, a key  enzyme in the biosynthesis of an anti-tumor polysaccharide from the  marine fungus Phoma herbarum YS4108. Process Biochem. 2011, 46, 2263–2268.

264. Zuo,  Z. K.; Wang, T.; Guo Y.; Song Y. C.; Tan, R. X.; Ge∗ H. M.; Cytotoxic  Angucyclines from Amycolatopsis sp. HCa1, a Rare Actinobacteria Derived  from Oxya chinensis. Planta Med. 2011, 77, 2057–2060.

263. Lin  A. J.; Mao H. B.; Zhu X.; Ge H. M.; Tan, R. X.; Zhu* C. J.; Cheng*Y.  X.; Organocatalytic enantioselective amination of Morita-Baylis-Hillman  carbonates with masked ammonia: a facile method for the synthesis of  unprotected α-Methylene--Amino esters. Chem. Eur. J. 2011, 17, 13676–13679.

262. Wu  Q.; Song*, Y. C.; Xu H.; Guo Y.; Li J.; Tan, R. X.* Medium optimization  for enhanced co-production of two bioactive metabolites in the same  fermentation by a statistical approach. J. Asian Nat. Prod. Res. 2011, 13, 1110–1121.

261. Dou  H.; Song Y. X.; Liu X. Q.; Gong W.; Li E. G.; Tan, R. X.*; Hou∗ Y. Y.  Chaetoglobosin Fex from the marine-derived endophytic fungus inhibits  induction of inflammatory mediators via Toll-Like receptor 4 signaling  in macrophages. Biol. Pharm. Bull. 2011, 34, 1864–1873.

260. Xu  H.; Jiang N.; Guo Y.; Jiao R. H.; Cui J. T.; Song Y. C.; Tan, R. X.*.  Fully substituted unsaturated lactones from endophytic Myrothecium sp. J. Asian Nat. Prod. Res. 2011, 13, 1003–1007.

259. Lin  A. J.; Mao H. B.; Zhu X.; Ge H. M.; Tan, R. X.; Zhu, C. J.; *  Cheng Y.  X.;* Organocatalytic asymmetric C–S bond formation: synthesis of  α-methylene--mercapto esters with simple alkyl thiols. Adv. Synth. Catal. 2011, 353, 3301–3306.

258. Chen  X. Q.; Wang Z. X.; Yang  Z. Y.; Wang J. J.; Xu Y. X.; Tan, R. X.; Li,  E. G.* Houttuynia cordata blocks HSV infection through inhibition of  NF-B activation. Antivir. Res. 2011, 92, 341–345.

257. Fun H. K.; Sudto, K.; Ge, H. M.; Tan, R. X., Hannongbua, S; Chantrapromma, S.*. Acta Crystallogr. 2011, E67, o1392–o1393.

256. Qin  Y. H.; Zhang J.; Cui J. T.; Guo Z. K.; Jiang N.; Tan, R. X, Ge, H. M.;* Oligostilbenes from Vatica mangachapoi with xanthine oxidase and  acetylcholinesterase inhibitory activities. RSC Adv. 2011, 1, 135–141.

255. Wu  X. F.; Wang Y. D.; Yu, S. S.; * Jiang N.; Ma J., Tan, R. X.; Hua Y. C.;  Qu J. Antioxidative acylphloroglucinols from the roots of Lysidice  rhodostegia. Tetrahedron. 2011, 67, 8155–8159.

254. Lin  A. J.; Wang J. Y. Mao H. B.; Ge H. M.; Tan, R. X., Zhu, C. J.; * Cheng,  Y. X.; * Organocatalytic asymmetric Michael-type/Wittig reaction of  phosphorus ylides: synthesis of chiral -methylene-δ-ketoesters. Org. Lett. 2011, 13, 4176–4179.

253. Du,  R. H.; Li, E. G.; Cao, Y.; Song, Y. C.; Tan, R. X.* Fumigaclavine C  inhibits tumor necrosis factor  production via suppression of toll-like  receptor 4 and nuclear factor B activation in macrophages. Life Sci. 2011, 89, 235–240.

252. Zhang  Y. L.; Zhang J.; Jiang N.; Lu Y. H.; Wang L.; Xu S. H.; Wang W.; Zhang  G. F.; Xu Q.; Ge H. M.; Ma J.; Song Y. C.; Tan, R. X.*.  Immunosuppressive polyketides from mantis-associated Daldinia  eschscholzii. J. Am. Chem. Soc. 2011, 133, 5931–5940.

251. Bi  S. F.; Li F.; Song Y. C.; Tan, R. X.; Ge, H. M.; * New acrylamide and  oxazolidin derivatives from a termite-associated Streptomyces sp. Nat.  Prod. Commun. 2011, 6, 353–355.

250. Zhang G. F.; Guo Z. K.;  Wang W.; Cui J. T.; Tan, R. X., Ge, H. M.;Neuraminidase inhibitory  terpenes from endophytic Cochliobolus sp. J. Asian Nat. Prod. Res. 2011,  13, 761–764.

249. Jiang N.; Tan, R. X., Ma, J.* Simulations  of solid-state vibrational vircular dichroism spectroscopy of  (S)-alternarlactam by using fragmentation quantum chemical calculations.  J. Phys. Chem. B. 2011, 115, 2801–2813.

248. 刘敏、谭仁祥、宋勇春新骨架免疫抑制剂产生菌IFB-TL01的鉴定.中国抗生素杂志. 2011, 36, 113–116及153.

247. Lin L.; Tan, R. X.* Cross-kingdom actions of phytohormones: a functional scaffold exploration. Chem. Rev. 2011, 111, 2734–2760.

246. Ge  H. M.; Yan W.; Guo Z. K.; Luo Q.; Feng R.; Zang L. Y.; Shen Y.; Jiao R.  H.; Xu Q.; Tan, R. X.* Precursor-directed Q1 fungal generation of novel  halogenated chaetoglobosins with more preferable immunosuppressive  action.Chem. Commun. 2011, 47, 2321–2323.

245. Ge H. M.;  Zhang Q.; Xu S. H.; Guo Z. K.; Song, Y . C.; Huang, W. Y.; Tan, R. X.*  Chaetoglocins A–D, four new metabolites from the endophytic fungus  Chaetomium globosum. Planta Med. 2011, 77, 277–280.


2010

244. Zhang,  A. H.; Jiang, N.; Gu, W.; Ma, J.; Wang, Y. R.; Song, Y. C.; Tan, R.  X.*. Characterization, synthesis and self-aggregation of  (-)-alternarlactam, a novel fungal cytotoxin with cyclopentenone and  isoquinolinone Scaffolds. Chem. Eur. J. 2010, 16,14479–14485.

243. Yuan,  W. H.; Liu, M.; Jiang, N.; Guo, Z . K.; Ma, J.; Zhang, J.; Song, Y. C.;  Tan, R. X.* Guignardones A–C: three meroterpenes from Guignardia   mangiferae. Eur. J. Org. Chem. 2010, 6348–6353.

242. Zhang,  J.; Ge, H. M.; Jiao, R. H.; Li, J.; Peng, H.; Wang, Y. R.; Wu, J. H.;  Song, Y. C.; Tan, R. X.* Cytotoxic chaetoglobosins from the endophyte Chaetomium globosum. Planta Med. 2010, 76, 1910–1914.

241. Zhang,  H. W; Zhang, J.; Hu, S.; Zhang, Z. J.; Zhu, C. J.; Ng, S. W.; Tan, R.  X.*. Ardeemins and cytochalasins from Aspergillus terreus residing in Artemisia annua. Planta Med. 2010, 76, 1616–1621.

240. Zhang,H.;  Liu, X. F.; Chen, S.; Wu, J. H.; Ye, X.; Xu, L. Z.; Chen, H. M.;Zhang,  D. P.; Tan, R. X.; Wang, Y. P.* Tectorigenin inhibits the in vitro  proliferation andenhancesmiR-338 expression of pulmonary fibroblasts in  rats with idiopathic pulmonary fibrosis.  J. Ethnopharmacol. 2010, 131, 165–173.

239. Wu,  J. H.; Wang, Y. R.; Huang, W. Y.; Tan, R. X.* Anti-proliferative and  pro-apoptotic effects of tectorigenin on hepatic stellate cells. World J. Gastroentero. 2010, 16, 3911–3918.

238. Shen,  J. S.; Wang, H. J.; Shen, Y. C.; Tan, R. X.* A new cytotoxic  trichothecene macrolide from the endophyte Myrothecium roridum. Planta Med. 2010, 76, 1004–1006.

237. Ge,  H. M.; Yang, W. H.; Shen, Y.; Jiang, N.; Guo, Z. K.; Xu Q.; Ma, J.;  Tan, R. X.* Novel and immunosuppressive resveratrol aneuploids from Hopea chinensis. Chem. Eur. J. 2010, 16, 6338–6345.

236. Wang,  Q. Z.; Ge, H. M.; Zhang, J.; Wu, J. H.; Song, Y. C.;Zhang, Y. F.; Tan,  R. X.*. Cochliones A-D, four new tetrahydrochromanone derivatives from  endophytic Cochliobolus sp.  J. Asian Nat. Prod. Res. 2010, 12, 485–491.

235. Wu,  X. F.; Hu, Y. C.; Yu, S. S.;* Jiang N., Ma, J.; Tan, R. X.; Li, Y.;  Lv,  H. N.; Liu, J.; Ma, S. G. Lysidicins F-H, three new phloroglucinols  from Lysidice rhodostegia. Org. Lett. 2010, 12, 2390–2393.

234. Ge, H. M.; Peng, H.; Guo, Z. K.; Cui, J. T.;  Song, Y. C., Tan, R. X.*. Bioactive alkaloids from the plant endophytic fungus Aspergillus terreus. Planta Med. 2010, 76, 822–824.

233. Chen, Z. G.*; Tan, R. X.; Huang, M. Efficient regioselective acylation of andrographolide catalyzed by immobilized Burkholderia cepacia lipase. Process Biochem. 2010, 45, 415–418.

232. Wang, F. W.; Ye, Y. H.; Ding, H.; Chen, Y. X.; Tan, R. X.; Song, Y. C.*. Benzophenones from Guignardia sp. IFB-E028, an Endophyte on Hopea hainanensis. Chem. Biodivers. 2010, 7, 216–220.


2009

231. Chen,   Z. G. *; Tan, R. X.; Cao, L. Efficient and highly regioselective   acylation of andrographolide catalyzed by lipase in acetone. Green Chem. 2009, 11, 1743–1745.

230. Chen,T.;Lin, X. Z.;Xu, J. F. Tan, R. X.;Ji, J. G.;Shen P. P.* Redox imbalance provokes deactivation of macrophages in sepsis. Proteom. Clin. Appl. 2009, 3, 1000–1009.

229. Yuan,W.   H.;Yi,Y. H.;Tan, R. X.;Wang,Z. L.; Sun,G.;Xue,Q.; Zhang, H. W.;  Tang,H.  F. * Antifungal triterpene glycosides from the sea cucumber Holothuria (Microthele) axiloga. Planta Med. 2009, 75, 647–653.

228. Ge, H. M.; Yang, W.; Zhang, J.; Tan, R. X.* Antioxidant oligostilbenoids from the stem wood of Hopea hainanensis J. Agric. Food Chem. 2009, 57, 5756–5761.

227. Xu, S.; Ge, H. M., Song, Y. C., Shen, Y.; Ding H.; Tan, R. X.* Cytotoxic cytochalasin metabolites of endophytic Endothia gyrosa. Chem. Biodivers. 2009, 6, 739–745.

226. Sang, Y. S.; Zhou, C. Y.; Lu, A. J.; Yin, X. J.; Min, Z. D.; Tan, R. X.*. Protolimonoids from Melia toosendan. J. Nat. Prod. 2009, 72, 917–920.

225. Shi,   D. H.;Wu, J. H.; Ge, H. M., Tan, R. X.* Protective effect of   hopeahainol A, a novel acetylcholinesterase inhibitor on hydrogen   peroxide-induced injury in PC12 cells. Environ. Toxicol. Pharm. 2009, 28, 30–36.

224. Ge, H. M.; Yu, Z. G.; Zhang, J.; Wu, J. H.; Tan, R. X.* Bioactive alkaloids from endophytic Aspergillus fumigatus. J. Nat. Prod. 2009, 72, 753–755.

223. Xu,   J. K.*; Wu, H. F.; Ang, E. S. M.; Yip, K.; Woloszyn, M. Zheng, M. H.   Tan, R. X. NF-kB modulators in osteolytic bone diseases. Cytokine Growth F. R. 2009, 20, 7–17.

222. Ge,   H. M.; Jiao, R. H.; Zhang, Y. F.; Zhang, J. Wang, Y. R.; Tan, R. X.*   Cytotoxicity and phytotoxicity of trichothecene macrolides from Myrothecium gramminum. Planta Med. 2009, 75, 227–229.

221. 戈惠明,谭仁祥∗. 共生菌——新活性天然产物的重要来源. 化学进展 2009, 21, 30–46.

220. Ge, H. M.; Tan, R. X. Symbionts, an important source of new bioactive natural products. Progress in Chemistry 2009, 21, 30-46.

219. Hu, S. C.; Hong, K.*; Song, Y. C.; Liu, J. Y.; Tan, R. X.* Streptomyces sp. 060524 and cytotoxicity of the products. World J. Microb. Biot. 2009, 25, 115–121.


2008

218. Zhang,  Y. L.; Ge, H. M.; Song, F. Li.; Song, Y. C., Tan, R. X.* New phytotoxic  metabolites from Pestalotiopsis sp. HC02, a Fungus Residing in  Chondracris rosee gut.  Chem. Biodivers. 2008, 5, 2402–2407.

217. Feng,  M. Q.; Zhou, T.; Wei, W. J.; Song, Y. C.; Tan, R. X.* Tn5  transposase-assisted high-efficiency transformation of filamentous  fungus Phoma herbarum YS4108. Appl. Microbiol. Biot. 2008, 80, 937–944.

216. Zhang,  H. W.; Huang, W. Y.; Chen, J. R.; Yan, W. Z.; Xie, D. Q.; Tan, R. X.*.  Cephalosol, an Antimicrobial Metabolite with an Unprecedented Skeleton  from Endophytic Cephalosporium acremonium IFB-E007. Chem. Eur. J. 2008, 14, 10670–10674.

215. Ge,  H. M.; Zhang, W. Y.; Ding, G.; Saparpakorn, P.; Song, Y. C.;  Hannongbua, S. Tan, R. X.* Chaetoglobins A and B, two unusual alkaloids  from endophytic Chaetomium globosum culture. Chem. Commun. 2008, 45, 5978–5980.

214. Shi,  D. H.; Xu, C.; Guo, B. X.; Wang, X. T.; Chen, Y. X.; Tan, R. X.*  Inhibition of soluble epoxide hydrolase by extracts derived from  inflammation-treating Chinese medicinal herbs. Phytother. Res. 2008, 22, 1264–1268.

213. 韩跃,谭仁祥,宋勇春∗. 海洋真菌多糖间接竞争ELISA检测方法的建立及方法学评价. 中国生化药物杂志 2008, 29, 221–224.

212. Han,  Y.; Tan, R. X.; Song, Y. C.*  Establishment and evaluation of indirect  competitive enzyme-linked immnunosorbent assay for detecting the  concentration of polysaccharide from marine fungus. Chinese Journal of Biochemical Pharmaceutics 2008, 29, 221–224.

211. Zhang,  Y. L.; Ge, H. M.; Zhao, W., Dong, H.; Xu, Q.; Li, S. H.; Zhang, J.;  Song, Y. C., Tan, R. X.* Unprecedented immunosuppressive polyketides  from Daldinia eschscholzii, a mantis-associated fungus. Angew. Chem. Int. Ed. 2008, 47, 5823–5826.

210. Gao,  X. X.; Ge, H. M.; Zhang, W. F.; Tan, R. X.* NMR-based metabonomics for  detection of Helicobacter pylori infection in gerbils: Which is more  descriptive. Helicobacter 2008, 13, 103–111.

209. Zheng,  L. P.; Guo, Y. Y.; Wang, J. W.*, Tan, R. X. Nitric oxide potentiates  oligosaccharide-induced artemisinin production in Artemisia annua hairy  roots. J. Integr. Plant Biol. 2008, 50, 49–55.

208. Ge,  H. M., Shen, Y., Zhu, C. H., Tang, S. H.; Ding,  H.; Song, Y. C.; Tan,  R. X.* Penicidones A-C, three cytotoxic alkaloidal metabolites of an  endophytic Penicillium sp. Phytochemistry 2008, 69, 571–576.

207. Ge, H. M.; Zhu, C. H.; Shi, D. H.; Yang, J.; Ng, S. W.; Tan, R. X.* Hopeahainol A, an acetylcholinesterase inhibitor from Hopea hainanensis. Chem. Eur. J. 2008, 14, 376–381.


2007

206. Li,   Y.; Shuang, J. L.; Yuan, W. W.; Huang, W. Y.; Tan, R. X.* Verticase: a   fibrinolytic enzyme produced by Verticillium sp. Tj33, an endophyte of  Trachelospermum jasminoide J. Integr. Plant Biol. 2007, 49, 1548–1554.

205. Wang, J. N.;  Gu, S. P.; Tan, R. X. Coumarin dimer and sesquiterpene lactones from Carpesium lipskyi Winkl. Indian J. Chem. 2007, 46B, 985–988.

204. Shi,   L.; Ge, H. M.; Tan, S. H.; Li, H. Q.; Song, Y. C.; Zhu, H. L.* Tan, R.   X. Synthesis and antimicrobial activities of Schiff bases derived from   5-chloro-salicylaldehyde. Eur. J. Med. Chem. 2007, 42, 558–564.

203. Wang,   J. W.; Zheng, L. P.; Tan, R. X.* Involvement of nitric oxide in   cerebroside-induced defense responses and taxol production in Taxus yunnanensis.Appl. Microbiol. Biot. 2007, 75, 1183–1190.

202. Huang,   X. F.; Ruan, B. F.; Wang, X. T.; Xu, C.; Ge, H. M.; Zhu, H. L.;*Tan,  R.  X.* Synthesis and cytotoxic evaluation of a series of resveratrol   derivatives modified in C2 position. Eur. J. Med. Chem. 2007, 42, 263–267.

201. Zhang,   L. N.; Xiao, Z. P.; Ding, H.; Ge, H. M., Xu, C.; Zhu, H. L. *;Tan, R.   X.*. Synthesis and cytotoxic evaluation of novel 7-O-modified Genistein   derivatives. Chem. Biodivers. 2007, 4, 248–255.

200. Gu,   W.; Ge, H. M.; Song, Y. C.; Ding, H.; Zhu, H. L.; Zhao, X. A.; Tan, R.   X.* Cytotoxic benzo[j]fluoranthene metabolites from Hypoxylon  truncatum  IFB-18, an endophyte of Artemisia annua. J. Nat. Prod. 2007, 70, 114–117.

199. Zheng,   W. F. *; Gao, X. W.; Chen, C. F.; Tan, R. X. * Total flavonoids of  Daphne  genkwa root significantly inhibit the growth and metastasis of  Lewis  lung carcinoma in C57BL6 mice. Int. Immunopharmacol. 2007, 7, 117–127.


2006

198. 王剑文*, 郑丽屏, 谭仁祥*.促进黄花蒿发根青蒿素合成的内生真菌诱导子的制备.生物工程学报 2006, 22, 829-834.

197. Wang,   J. W. *; Zheng, L. P.; Tan, R. X.* The preparation of an elicitor from  a  fungal endophyte to enhance artemisinin production in hairy root   cultures of Artemisia annua L. Chinese Journal of Biotechnology 2006, 22, 829–834.

196. Ge, H. M.; Huang, B.; Tan, S. H.; Shi, D. H.; Song, Y. C.; Tan, R. X.* Bioactive oligostilbenoids from the stem bark of Hopea exalata. J. Nat. Prod. 2006, 69, 1800–1802.

195. Ge, H. M.; Xu, C.; Wang, X. T.; Huang, B.; Tan, R. X.* Hopeanol: a potent cytotoxin with a novel skeleton from Hopea exalata. Eur. J. Org. Chem. 2006, 2006, 5551–5554.

194. Wang,   J. W.∗; Zheng, L. P.; Wu, H. Y.; Tan, R. X.. Involvement of nitric   oxide in oxidative burst, phenylalanine ammonia-lyase activation and   Taxol production induced by low-energy ultrasound in Taxus yunnanensis   cell suspension cultures.  Nitric Oxide – Biol. Ch. 2006, 15, 351–358.

193. Jiao,   R. H.; Xu, S.; Liu, J. Y.; Ge, H. M.; Ding, H.; Xu, C.; Zhu, H. L.;   Tan, R. X.*. Chaetominine, a cytotoxic alkaloid produced by endophytic Chaetomium sp. IFB-E015. Org.  Lett. 2006, 8, 5709–5712.

192. Ruan,   B. F.; Huang, X. F.; Ding, H.; Xu, C.; Ge, H. M.; Zhu, H. L.*; Tan, R.   X.∗. Synthesis and cytotoxic evaluation of a series of resveratrol   derivatives. Chem. Biodiver. 2006, 3, 975–981.

191. Tan, R. X. Editorial: Natural products chemistry in China. Nat. Prod. Rep. 2006, 23, 667–668 (editorial).

190. Zhang, H. W.; Song, Y. C.; Tan, R. X.* Biology and chemistry of endophytes. Nat. Prod. Rep. 2006, 23, 753–771.

189. Wang,   F. W.; Ye, Y. H.; Chen, J. R.; Wang, X. T.; Zhu, H. L.; Song, Y. C.*;   Tan, R. X.. Neoplaether, a new cytotoxic and antifungal endophyte   metabolite from Neoplaconema napellum IFB-E016. FEMS Microbiol. Lett. 2006, 261, 218–223.

188. Liu, C. H.* ; Mishra, A. K. ; Tan, R. X.. Repellent, insecticidal and phytotoxic activities of isoalantolactone from Inula racemosa. Crop Prot. 2006, 25, 508–511.

187. Ma,   H. Y.; Song, Y. C.; Mao, Y. Y.; Tan, R. X.; Luo, L.* Endophytic fungal   metabolite fumigaclavine C causes relaxation of isolated rat aortic   rings. Planta Med. 2006, 72, 387–392.

186. Shen, L.;   Jiao, R. H.; Ye, Y. H.; Wang, X. T.; Song, C.; Xu, Y. C.; Zhu, H. L.*,   Tan, R. X.*. Absolute configuration of new cytotoxic and other  bioactive  trichothecene macrolides. Chem. Eur. J. 2006, 12, 5596–5602.

185. Shen,   L.; Ye, Y. H.; Wang, X. T.; Zhu, H. L.*, Xu, C.; Song, Y. C.; Li, H.;   Tan, R. X.* Structure and total synthesis of aspernigerin: a novel   cytotoxic endophyte metabolite. Chem. Eur. J. 2006, 12, 4393–4396.

184. Li,   H. Q.; Ge, H. M.; Chen, Y. X.; Xu, C.; Shi, L.; Ding, H.; Zhu, H.   L.*;Tan, R. X.∗. Synthesis and cytotoxic evaluation of a series of   genistein derivatives. Chem. Biodivers. 2006, 3, 463–472.

183. Ge, H. M.; Song, Y. C.; Chen, J. R.; Hu, S.; Wu, J. Y.; Tan, R. X.*. Paranolin: a new xanthene-based metabolite from Paraphaeosphaeria nolinae. Helv. Chim. Acta 2006, 89, 502–506.

182. He,   L.*; Kong, E J.; Liu, Y. M.; An, Y.; Zhang, W. S.; Shi, D. H.; Tan, R.   X.*. Synthesis and biological activity of flavane derivatives. Chiense Journal of Chemistry 2006, 24, 401–408.

181. Liu, L. G.*; Tan, R. X.; Gong, Y. M. New jatrophane diterpenoid ester from Euphorbia turczaninowii. Chinese Chem. Lett. 2006, 17, 201–203.

180. Ding,   G.; Song, Y. C.; Chen, J. R.; Xu, C.; Ge, H. M.; Wang, X. T.; Tan, R.   X.* Chaetoglobosin U, a cytochalasan alkaloid from endophytic Chaetomium globosum IFB-E019.  J. Nat. Prod. 2006, 69, 302–304.

179. Liu,   C. H.*; Mishra, A. K.; Tan, R. X.; Tang, C.; Yang, H.; Shen, Y. F..   Repellent and insecticidal activities of essential oils from Artemisia   princeps and Cinnamomum camphora and their effect on seed germination  of  wheat and broad bean. Bioresource Technol. 2006, 97, 1969−1973.

178. Wang, J. W.; Wu, J. H.; Huang, W. Y.; Tan, R. X.* Laccase production by Monotospora sp., an endophytic fungus in Cynodon dactylon. Bioresource Technol. 2006, 97, 786–789.

177. 谭仁祥*.海洋微生物:新天然药物的重要源泉.中国天然药物  2006, 4, 2-4.

176. Tan, R. X.* Marine microbes: an important source of new natural medicines.Chinese Journal of Natural Medicines 2006, 4, 2–4.

175. Liu,   J. Y.; Huang, L. L.; Ye, Y. H.; Zou, W. X.; Guo, Z. J.; Tan, R. X.*   Antifungal and new metabolites of Myrothecium sp. Z16, a fungus   associated with white croaker Argyrosomus argentatus.  J. Appl. Microbiol. 2006, 100, 195–202.

174. Wu,   J. H.; Xu, C.; Shan, C. Y.; Tan, R. X.* Antioxidant properties and  PC12  cell protective effects of APS-1, a polysaccharide from Aloe vera var. chinensis. Life Sci. 2006, 78, 622–630.

173. Wang, S. F.; Ye, Y. H.; Zhang, Z.; Tan, R. X.*. Regioselective sonochemical synthesis of genistein derivatives. Ultrason. Sonochem. 2006, 13, 28–31.


2005

172. Ge,   H. M.; Song, Y. C.; Shan, C. Y.; Ye, Y. H.; Tan, R. X.* New and   cytotoxic anthraquinones from Pleospora sp. IFB-E006, an endophytic   fungus in Imperara cylindrical. Planta Med. 2005, 71, 1063–1065.

171. Zhang   H. W.; Huang W. Y.; Song Y. C.; Chen J. R.; Tan R. X.* Four   6H-dibenzo[b,d]pyran-6-one derivatives produced by the endophyte Cephalosporium acremonium IFB-E007.Helv. Chim. Acta 2005, 88, 2861–2864.

170. Liu, J. Y.; Ye, Y. H.; Wang, L.; Shi, D. H.; Tan, R. X.* New resveratrol oligomers from the stem bark of Hopea hainanensis.Helv. Chim. Acta 2005, 88, 2910–2917.

169. Yan, Q.; Hu, Z. D.; Tan, R. X.; Wu, J. Y.* Efficient production and recovery of diterpenoid tanshinones in Salvia miltiorrhiza hairy root cultures with in situ adsorption, elicitation and semi-continuous operation. J. Biotechnol. 2005, 119, 416–424.

168. Chen, H.; Xu, C.; Liu, D. Q.; An, S. Q.; Tan, R. X.* Buddlin, a new compound from Buddleja asiatica. Fitoterapia 2005, 76, 588–589.

167. Yang,   X. B.; Gao, X. D.*; Han, F.; Tan, R. X.* Sulfation of a polysaccharide   produced by a marine filamentous fungus Phoma herbarum YS4108 alters  its  antioxidant properties in vitro. BBA-Gen. Subjects 2005, 1725, 120–127.

166. Wang,   S. F.; Jiang, Q.; Ye, Y. H.; Li, Y.; Tan, R. X.* Genistein derivatives   as selective estrogen receptor modulators: sonochemical synthesis and  in  vivo anti-osteoporotic action. Bioorg. Med. Chem. 2005, 13, 4880–4890.

165. Ye,   Y. H.; Zhu, H. L.; Song, Y. C.; Liu, J. Y.; Tan, R. X.* Structural   revision of aspernigrin A, reisolated from Cladosporium herbarum   IFB-E002. J. Nat. Prod. 2005, 68, 1106–1108.

164. Yang,   X. B.; Gao, X. D.*; Han, F.; Xu, B. S.; Song, Y. C.; Tan, R. X.*   Purification, characterization and enzymatic degradation of YCP, a   polysaccharide from marine filamentous fungus Phoma herbarum YS4108. Biochimie 2005, 87, 747–754.

163. Wu,   X. F.; Fei, M. J.; Shu, R. G.; Tan, R. X.; Xu, Q.* Fumigaclavine C, a   fungal metabolite, improves experimental colitis in mice via   downregulating Th1 cytokine production and matrix metalloproteinase   activity. Int. Immunopharmacol. 2005, 5, 1543–1553.

162. Li, Y.; Song, Y. C.; Liu, J. Y.; Ma, Y. M.; Tan, R. X.* Anti-Helicobacter pylori substances from endophytic fungal cultures. World J. Microb. Biot. 2005, 21, 553–558.

161. Hu, S. C.; Tan, R. X.*; Hong, K.*; Yu, Z. N.*; Zhu, H. L. Methyl indole-3-carboxylate. Acta Crystallogr. 2005, E61, o1654–1656.

160. Wang,   X. N.; Tan, R. X.; Liu, J. K.* Xylactam, a new nitrogen-containing   compound from the fruiting bodies of Ascomycete Xylaria euglossa. J. Antibiot. 2005, 58, 268–270.

159. Wang,   X. N.; Tan, R. X.; Wang, F.; Steglich, W.; Liu, J. K.* The first   isolation of a phlegmacin type pigment from the Ascomycete Xylaria   euglossa. Z. Naturforsch. 2005, 60B, 333–336.

158. Song,   Y. C.; Huang, W. Y.; Sun, C.; Wang, F. W.; Tan, R. X.*  Characterization  of graphislactone a as the antioxidant and free  radical-scavenging  substance from the culture of Cephalosporium sp.

157. 1FB-E001, an endophytic fungus in Trachelospermum jasminoides. Biol. Pharm. Bull. 2005, 28, 506–569.

156. Li,   Y.; Xu, C.; Zhang, Q.; Liu, J. Y.; Tan, R. X.* In vitro   anti-Helicobacter pylori action of thirty Chinese herbal medicines used   to treat ulcer diseases. J. Ethnopharmacol. 2005, 98, 329–333.

155. Xu, C.; Zhang, J. S.; Mo, Y.; Tan, R. X.* Calcium pectinate capsules for colon-specific insulin delivery  Drug Dev. Ind. Pharm. 2005, 31, 127–134.

154. Shu, R. G.; Zhu, H. L.; Tan, R. X.* Methyl 5-hydroxy-2-(2-hydroxy-6-methoxy-4-methylbenzoyl)-3-methoxybenzoate. Acta Crystallogr. 2005, E61, o189–o191.

153. Sun,   C.; Shan, C. Y.; Gao, X. D.; Tan, R. X.* Protection of PC12 cells from   hydrogen peroxide-induced injury by EPS2, an exopolysaccharide from a   marine filamentous fungus Keissleriella sp. YS4108. J. Biotechnol.  2005,  115, 137–144.


2004

152. Shu,  R. G.; Wang, F. W.; Yang, Y. M.; Liu, Y. X.; Tan, R. X.* Antibacterial  and Xanthine Oxidase Inhibitory Cerebrosides from Fusarium sp. IFB-121,  an Endophytic Fungus in Quercus variabilis. Lipids ,2004, 39, 667–673.

151. Song,  Y. C.; Li, H.; Ye, Y. H.; Shan, C. Y.; Yang, Y. M.; Tan, R. X.*  Endophytic naphthopyrone metabolites are co-inhibitors on xanthine  oxidase, SW1116 cell and some microbial growths. FEMS Microbiol. Lett. 2004, 241, 67–72.

150. Liu,  J. Y.; Song, Y, C.;Zhang, Z.;Wang, L.; Guo, Z. J.; Tan, R. X.* New and  bioactive metabolites from Aspergillus fumigatus CY018, an endophytic  fungus harboring in Cynodon dactylon. J. Biotechnol. 2004, 114, 279–287.

149. Tan,  R. X.; Jensen, P. R.; Williams, P. G.; Fenical, W.* solation and  structure assignments of rostratins A-D, cytotoxic disulfides produced  by the marine-derived fungus Exserohilum rostratum. J. Nat. Prod. 2004, 67, 1374–1382.

148. Luo,  L.; Sun, Q.; Mao, Y. Y.; Lu, Y. H.; Tan, R. X.* Inhibitory effects of  flavonoids from Hypericum perforatum on nitric oxide synthase. J. Ethnopharmacol. 2004, 93, 221–225.

147. Ma,  Y. M.; Li, Y.; Liu, J. Y.; Song, Y. C., Tan, R. X.* Anti-Helicobacter  pylori metabolites from Rhizoctonia sp. Cy064, an endophytic fungus in Cynodon dactylon. Fitoterapia 2004, 75, 451–456.

146. Yang,  Y. M.*; Gu, X. S.; Tan, R. X.; Hu, W.; Wang, X. D.; Zhang, P. Y.;  Zhang, T. Y. Fabrication and properties of a porous chitin/chitosan  conduit for nerve regeneration. Biotechnol. Lett. 2004, 26, 1793–1797.

145. Sun,  C.; Wang, J. W.; Fang, L.; Gao, X. D.; Tan, R. X.* Free radical  scavenging and antioxidant activities of EPS2, an exopolysaccharide  produced by a marine filamentous fungus Keissleriella sp. YS 4108. Life Sci. 2004, 75, 1063–1073.

144. Zhao,  Y.; Liu, J. Y.; Wang, J.; Wang, L.; Yin, H.; Tan, R. X.; Xu, Q.*  Fumigaclavine C improves concanavalin A-induced liver injury in mice  mainly via inhibiting TNF- production and lymphocyte adhesion to  extracellular matrices. J. Pharm. Pharmacol. 2004, 56, 775–782.

143. Kong,  L. D.; Christopher H.; Cheng, K.; Tan, R. X.* Inhibition of MAO A and B  by some plant-derived alkaloids, phenols and anthraquinones. J. Ethnopharmacol. 2004, 91, 351–355.

142. Xu, C.; Luo, L.; Tan, R. X.* Antidepressant effect of three traditional Chinese medicines in the learned helplessness model. J. Ethnopharmacol. 2004, 91, 345–349.

141. Wang,  J. W.; Xia, Z. H.; Chu, J. H.; Tan, R. X.* Simultaneous production of  anthocyanin and triterpenoids in suspension cultures of Perilla  frutescens. Enzym. Microbiol. Technol. 2004, 34, 651–656.

140. Xu, C.; Zhang, Y.; Tan, R. X.* A new oxoaporphine alkaloid from Sinofranchetia chinensis. Fitoterapia 2004, 75, 239–241.

139. Ji,  L. L.;Song, Y. C.; Tan, R. X.* A potent feed preservative candidate  produced by Calcarisporium sp., an endophyte residing in stargrass  (Cynodon dactylon) J. Appli. Microbiol. 2004, 96, 352–358.

138. Yang, Y. M.; Wang, J. W.; Tan, R. X.* mmobilization of glucose oxidase on chitosan–SiO2 gel.  Enzym. Microbiol. Technol. 2004, 34, 126–131.

137. Cui,  G. Y.; Tan, R. X.* Lignans and tannins from Alchornea davidii Franch.  (Euphorbiaceae) and their chemotaxonomic significance. Biochem. Syst. Ecol. 2004, 32, 99–102.


2003

136. 王剑文,邹文欣,谭仁祥*. 黄花蒿内生菌的化学和生物学研究. 中草药 2003, 34(S), 78–81.

135. Wang, J. W.; Zou, W. X.; Tan, R. X.* Chemical and biological investigation of endophytes in Artemisia annua. Chinese Traditional and Herbal Drugs 2003, 34, 78-81.

134. Tan, R. X.*; Chen, J. H. The cerebrosides Nat. Prod. Rep. 2003, 20, 509–534.

133. Chen, J. H.; Xia, Z. H.; Tan, R. X.* High-performance liquid chromatographic analysis of bioactive triterpenes in Perilla frutescens. J. Pharmaceut. Biomed. 2003, 32, 1175–1179.

132. Zhou,  C. X.; Liu, J. Y.; Ye, W. C.; Liu, C. H.; Tan, R. X.* Neoverataline A  and B, two antifungal alkaloids with a novel carbon skeleton from Veratrum taliense. Tetrahedron 2003, 59, 5743–5747.

131. Liu,  C. H.; Liu, J. Y.; Huang, L. L.; Zou, W. X.; Tan, R. X.* Absolute  configuration of keisslone, a new antimicrobial metabolite from  Keissleriella sp. YS4108, a marine filamentous fungus. Planta Med. 2003, 69, 481–483.

130. Gao,  X. D.; Ye, W. C.; Yu, A. C.; Yu, H., Zhang, Y.; Tan, R. X.; Li, M.;  Hsiao, W. L. W. * Pulsatilloside A and anemoside A(3) protect PC12 cells  from apoptosis induced by sodium cyanide and glucose deprivation. Planta Med. 2003, 69, 171–174.

129. Liu,  J. Y.; Liu, C. H.; Zou, W. X.; Tan, R. X.* Leptosphaeric acid, a  metabolite with a novel carbon skeleton from Leptosphaeria sp. IV403, an  endophytic fungus in Artemisia annua. Helv. Chim. Acta 2003, 86, 657–660.

128. Wang, X. Y. *; Tan, R. X.; Guo, Z. J. Syntheses of 1,4,7,10-tetraazacyclododecane and its derivatives. ChineseJ. Org. Chem. 2003, 23, 129–138.

127. Wang,  X. Y.; Lin, J.; Zhang, X. M.; Liu, Q.; Xu, Q.; Tan, R. X.; Guo, Z. J.*  5-Fluorouracil-cisplatin adducts with potential antitumor activity. J. Inorg. Biochem. 2003, 94, 186–192.

126. Cui, G. Y.; Liu, J. Y.; Tan, R. X.* new antimicrobial flavonol glycoside from Alchornea davidii. Chinese Chem. Lett. 2003, 14, 179–180.

125. Chen, J. H.; Cui, G. Y.; Liu, J. Y.; Tan, R. X.* Pinelloside, a new antimicrobial cerebroside from Pinellia ternata. Phytochemistry 2003, 64, 903–906.


2002

124. 建农, 谭仁祥*. 野艾蒿地上部分化学成分的分离与结构鉴定. 中草药 2002, 33(S), 61–63.

123. Wang,  J. N.; Tan, R. X.*. Isolation and identification of the chemical  constituents of the aerial parts of Artemisia lavandulaefolia. Chinese Traditional and Herbal Drugs 2002, 33(S), 61–63.

122. Wang,  J. W.; Kong, F. X.; Tan, R. X.* Improved artemisinin accumulation in  hairy root cultures of Artemisia annua by (22S, 23S)-homobrassinolide. Biotechnol. Lett. 2002, 24, 1573–1577.

121. Cai, Y.; Jiang, J. G.; Liu, C. H.; Kong, L. D.; Tan, R. X.Composition and antifungal activity of essential oil from Perilla frutescens leaves. International Pest Control. 2002, 44, 66–68.

120. Wang,  J. W.; Xia, Z. H.; Tan, R. X.* Elicitation on artemisinin biosynthesis  in Artemisia annua hairy roots by the oligosaccharide extract fron the  endophytic Colletotrichum sp. B501. Acta Botanica Sinica 2002, 44, 1233–1238. (植物学报英文版)

119. Liu,  J. Y.; Liu, C. H.; Zou, W. X.; Tian, X.; Tan, R. X.* Leptosphaerone, a  metabolite with a novel skeleton from Leptosphaeria sp. IV403, an  endophytic fungus in Artemisia annua. Helv. Chim. Acta 2002, 85, 2664–2667.

118. Yang,  L.; Tan, R. X.*; Wang, Q.*; Huang, W. Y.; Yin, Y. X. Antifungal  cyclopeptides from Halobacillus litoralis YS3106 of marine origin. Tetrahedron Lett. 2002, 43, 6545–6548.

117. Wang,  J. W.; Tan, R. X.* Artemisinin production in Artemisia annua hairy root  cultures with improved growth by altering the nitrogen source in the  medium. Biotechnology Letters 2002, 24, 1153–1156.

116. Lu, Y. H.; Zhang, Z.; Shi, G. X.; Meng, C. Tan, R. X.* A new antifungal flavonol glycoside from Hypericum perforatum.Acta Botanica Sinica 2002, 44, 743–745. (植物学报英文版)

115. Liu,  C. H.; Meng, J. C.; Zou, W. X.; Huang, L. L.; Tang, H. Q.; Tan, R. X.*  Antifungal metabolite with a new carbon skeleton from Keisslerriella sp. YS4108, a marine filamentous fungus. Planta Med. 2002, 68, 363–365.

114. Liu, L. G.; Meng, J. C.; Wu, S. X.; Li, X. Y.; Zhao, X. C.; Tan, R. X.* New macrocyclic diterpenoids from Euphorbia esula. Planta Med. 2002, 68, 244–248.


2001

113. Liu, C. H.; Mishra, A. K.; He, B.; Tan, R. X.* Composition and bioactivity of essential oils from Artemisia princeps and Cinnamomum camphora. International Pest Control 2001, 43, 72–74.

112. Meng J. C.; Hu Y. F.; Chen J. H.; Tan, R. X.*. Antifungal highly oxygenated guaianolides and other constituents from Ajania fruticulosa. Phytochemistry 2001, 58, 1141–1145.

111. Kong L. D.; Abliz Z.; Zhou C. X.; Li L. J.; Cheng C. H. K.; Tan, R. X.*. Glycosides and xanthine oxidase inhibitors from Conyza bonariensis.Phytochemistry 2001, 58, 645–651.

110. 邹文欣,谭仁祥*. 植物内生菌研究新进展. 植物学报 2001, 43, 881–892.

109. Zou W. X.; Tan, R. X.* Recent advances on endophyte research. Acta Botanica Sinica 2001, 43, 881–892.

108. Luo  L.; Tan, R. X.*. Luoxetine inhibits dendrite atrophy of hippocampal  neurons by decreasing nitric oxide synthase expression in rat depression  model. Acta Pharmacol. Sin. 2001, 22, 865–870.

107. Liu L. G.; Tan, R. X.*. New jatrophane diterpenoid esters from Euphorbia turczaninowii. J. Nat. Prod. 2001, 64, 1064–1068.

106. Tan, R. X.*; Zou W.X. Endophytes: a rich source of functional metabolites Nat. Prod. Rep. 2001, 18, 448–459.

105. Liu  C. H.; Zou W. X.; Lu H.; Tan, R. X.*. Antifungal activity of Artemisia  annua endophyte cultures against some phytopathogenic fungi. J. Biotechnol. 2001, 88, 277–283.

104. Wang  J. W.; Zhang Z.; Tan, R. X.*. Stimulation of artemisinin production in  Artemisia annua hairy roots by the elicitor from the endophytic Colletotrichum sp. Biotechnol. Lett. 2001, 23, 857–860.

103. Liu C. H.; Mishra A. K.; He B.; Tan, R. X.* Antimicrobial activities of isoalantolactone, a major sesquiterpene lactone of Inula racemosa. Chin. Sci. Bull. 2001, 46, 498–501.

102. Zhang W. Y.; Chen H.; Wang S. J.; Xia Z. H; Fei X. G.; Tan, R. X.* An acidic polysaccharide from Porphyra yezoensis. Chin. Sci. Bull. 2001, 46, 207–210.

101. Kong  L. D.; Tan, R. X.; Woo A. Y. H.; Cheng C. H. K. * Inhibition of rat  brain monoamine oxidase activities by psoralen and isoporalen:  implications for the treatment of affective disorders.

100. Pharmacology & Toxicology 2001, 88, 75–80.【现刊名:Basic & Clinical Pharmacology & Toxicology】

99. hou C. X.; Kong L. D.; Ye W. C.; Tan, R. X. Inhibition of xanthine and monoamine (type A) oxidases by stilbenoids from Veratrum taliense. Planta Med. 2001, 67, 158–161.

98. Kong L L. D.; Cheng C. H. K.; Tan, R. X.* Monoamine oxidase inhibitors from rhizoma of Coptis chinensis. Planta Med. 2001, 67, 74–76. 


2000年以前

97. 谭仁祥*,杨玲. 浅谈海洋药物研究与开发战略. 中国新药杂志 2000, 9, 435–437.

96. Tan, R. X.*; Yang L.: The suggested strategy for the research and development of marine-originated drugs. Chinese New Drugs Journal 2000, 9, 435–437.

95. 卢艳花∗; 谭仁祥. 抗抑郁天然药物的研究进展. 中草药 2000, 31, 718–720.

94. Lu Y. H.; Tan, R. X. The progress in the natural antidepressant drug researches. Chinese Traditional and Herbal Drugs 2000, 31, 718–720.

93. Mishra  A. K.; Liu C. H.; He B.; Tan, R. X.* fficacy of isoalantolactone, a  sesquiterpene lactone from Inula racemosa, as herbal fungitoxicant to  control ‘take-all’ disease of wheat. International Pest Control 2000, 42, 131–133 and 137.

92. Meng J. C.; Tan, R. X.*. Ajanoside, a xanthine oxidase inhibitor with a novel skeleton from Ajania fruticulosa. Chem. Lett. 2000, 12, 1418–1419.

91. Tan,  R. X.; Meng J. C.; Hostettmann K. * Phytochemical investigation of some  traditional Chinese medicines and endophyte cultures. Pharm. Biol. 2000, 38(S), 25–32.

90. Hu  Y. Q. *; J Guo. X.; Wang L. J.; Tan, R. X.; Zhen L. Y. Preparation and  evaluation of insulin-loaded polylactide microspheres using factorial  design. Drug Dev. Ind. Pharm. 2000, 26, 1309–1313.

89. Zou  W. X.; Lu H.; Meng J. C.; Chen G. X.; Zhang T. Y.; Tan, R. X.* New and  bioactive metabolites of Colletotrichum gloeosporioides, an endophytic  fungus in Artemisia mongolica. J. Nat. Prod. 2000, 63, 1529–1530.

88. Luo  L.; Wang J. N.; Kong L. D.; Jiang Q. G.; Tan, R. X.*. Antidepressant  effects of Banxia Houpu decoction, a traditional Chinese medicinal  empirical formula. J. Ethnopharmacol. 2000, 73, 277–281.

87. Wang Q.; Terreaux C.; Marston A.; Tan, R. X.; Hostettmann K. * Lignans from Mosla scabra. Phytochemistry 2000, 54, 909–912.

86. Kong  L. D.; Cai Y.; Huang W. W.; Cheng C. H. K.; Tan, R. X.*. Inhibition of  xanthine oxidase by some Chinese medicinal plants used to treat gout. J. Ethnopharmacol. 2000, 73, 199–207.

85. Pan  X.; Kong L. D.; Zhang Y.; Cheng Christopher H. K.; Tan, R. X.* In vitro  inhibition of monoamine oxidase by liquiritigenin and isoliquiritigenin  isolated from Sinofranchetia chinensis. Acta Pharmacol. Sin. 2000, 21, 949–953.

84. Meng J. C.; Zhu Q. X.; Tan, R. X.*. Planta Med. 2000, 66, 541–544.

83. Wang  J. N. *; Hano Y.; Normura T.; Chen Y. J.; Tan, R. X.. New Antimicrobial  mono- and sesquiterpenes from Soroseris hookeriana subsp. erysimoides. Acta Pharmacol. Sin. 2000, 21, 633–636.

82. Tang  H. Q.; Hu J.; Yang L.; Tan, R. X.* Antioxidative action of procyanidins  from the seeds of Vitis amurensis. Terpenoids and Flavonoids from Artemisia species. Planta Med. 2000, 66, 391–393.

81. Kong  L. D.; Zhang Y.; Pan X.; Tan, R. X.; Cheng Christopher H. K. *.  Inhibition of xanthine oxidase by liquiritigenin and isoliquiritigenin  isolated from Sinofranchetia chinensis. Cell. Mol. Life Sci. 2000, 57, 500–505.

80. Zhou C. X.; Tan, R. X.*; Ye W. C.; Min Z. D. Steroidal alkaloids from Veratrum taliense. Indian J. Chem. 2000, 39B, 283–286.

79. Hu  Y. Q.; Tan, R. X.*; Chu M. Y.; Zhou J.Apoptosis in human hepatoma cell  line SMMC-7721 induced by the water-soluble macromolecule ingredients of  Artemisia capillaris Thunb. Jpn. J. Cancer Res. 2000, 91, 113–117.

78. Lu  H.; Zou W. X.; Meng J. C.; Hu J.; Tan, R. X.* New bioactive metabolites  produced by Colletotrichum sp., an endophytic fungi in Artemisia annua. Plant Sci. 2000, 151, 67–73.

77. Liu  C. H. *; Shang H. S.; Tan, R. X. Infection process of take-all causing  fungus (Gaeumannomyces graminis var. tritici) on wheat and oat roots. Indian J. Agr. Sci. 2000, 70, 23–27.

76. 胡一桥*, 谭仁祥, 褚明艳, 欧文星. 茵陈粗多肽的提取分离及小鼠肝保护作用. 中草药 1999, 30, 894–896.

75. Hu,  Y. Q.; Tan, R. X.; Zhu, M. Y.; Ou, W. X. The separation and  hepatoprotective effect of crude polypeptides from Artemisia  capillaries. Chinese Traditional and Herbal Drugs 1999, 30, 894–896.

74. 胡一桥*, 郭建新,郑梁元,谭仁祥. 胰岛素聚乳酸微球处方筛选. 中国药学杂志 . 1999, 34, 822–826.

73. Hu, Y. Q.; Guo, J. X.; Zheng, L. Y.; Tan, R. X. Insulin polylactic acid microspheres prescription screening.Chinese Journal of Pharmacy 1999, 34, 822–826.

72. 王建农∗,谭仁祥. 药用蒿属植物的研究进展. 中草药 1999, 30(增刊): 33–35.

71. Wang, J. N.; Tan, R. X. Recent investigation of medicinally used Artemisia species. Chinese Traditional and Herbal Drugs 1999, 30(S): 33–35.

70. Wang,  Q.; Terreaux, C.; Marston, A.; Tan, R. X.; Stoeckli-Evans, H.;  Hostettmann, K. * Hostettmann*. A new 2-hydroxyflavone from Mosla soochouensis. Planta Med. 1999, 65, 729–731.

69. Meng,  J. C.; Lu, H.; Li, H.; Yang, L.; Tan, R. X.* A new antibacterial  sesquiterpene glycoside and other bioactive compounds from Biebersteinia heterostemon. Spectrosc. Lett. 1999, 32, 1005–1012.

68. Kong, L. D.; Wolfender, J. L.; Christopher H.; Cheng, K.; Hostettmann K. *; Tan, R. X.* Xanthine oxidase inhibitors from Brandisia hancei. Planta Med. 1999, 65, 744–746.

67. Lu, H.; Hu, J.; Zhang, L. X.; Tan, R. X.* Planta Med. 1999, 65, 586–587.

66. Chen,  H.; Zhang, X.; Xia, Z. H.; Liu, D. Q.; Yang, L.; Liu, Z. L.; Tan, R.  X.∗ Two new clerodane diterpenes with antibacterial activity from Ajuga lupulina. Indian J. Chem. 1999, 38B, 743–745.

65. Li,  H.; Meng, J. C.; Cheng, C. H. K.; Higa, T.; Tanaka, J.; Tan, R. X.* New  guaianolides and xanthine oxidase inhibitory flavonols from Ajania fruticulosa. J. Nat. Prod. 1999, 62, 1053–1055.

64. Zhou, C. X.; Tanaka, J.; Cheng, C. H. K.; Higa, T.; Tan, R. X.* Steroidal alkaloids and stilbenoids from Veratrum taliense. Planta Med. 1999, 65, 480–482.

63. Hu, Y. Q.; Qian, C. Q.; Zheng, L. Y.; Yu, W. H.; Tan, R. X.∗ Intestinal absorption of cefixime in rats. Acta Pharmacol. Sin. 1999, 20, 55–58.

62. Huang, H.; Chao, Q. R.; Tan, R. X.*; Sun, H. D.; Wang, D. C.; Zhao, S. X. A new rosmarinic acid derivative from Isodon oresbius. Planta Med. 1999, 65, 92–93.

61. Tan,  R. X.*, Lu, H; Wolfender, J. L.; Yu, T. T.; Zheng, W. F.; Yang, L.;  Gafner, S.; Hostettmann, K. ∗ Mono- and sesquiterpenes and antifungal  constituents from Artemisia species Planta Med. 1999, 65, 64–67.

60. 范以梅,王勇,谭仁祥,张祖暄. 银杏叶黄酮甙含量与生长季节和植株性别的相关性研究. 中国中药杂志 1998, 23, 267–269.

59. Fan, Y. M.; Wang, Y.; Tan, R. X.; Zhang, Z. X.; Seasonal and sexual variations in the content of flavone glycosides. Chinese Journal of Traditional Medicine 1998, 23, 267–269.

58. Huang, H. Q.; Chao, R.; Hu, J.; Tan, R. X.∗ Structure of oresbiuside from Isodon oresbius. Spectrosc. Lett. 1998, 31, 1635–1641.

57. Tan, R. X.*; Tang, H. Q.; Hu, J.; Shuai, B.; Sesquiterpene lactones from Artemisia sieversiana and Inula racemosa. Phytochemistry 1998, 49, 157–161.

56. Tan, R. X.*; Zhang, W. F.; Tang, H. Q. Biologically active substances from Artemisia L  Planta Med. 1998, 64, 295–302.

55. Tan, R. X.*; Ma, W. G.; Wei, H. X.; Zhang, L. X.; Glycosides from Wahlenbergia marginata. Phytochemistry 1998, 48, 1245–1250.

54. Tan, R. X.*; Kong, L. D.; Wei, H. X. Secoiridoid glycosides and antifungal anthranilate from Gentiana tibetica. Phytochemistry 1998, 47, 1223–1226.

53. Zhao,  Y.; Parsons, S.; Smart, B. A. Tan, R. X.; Jia, Z. J.; Sun, H. D.;  Rankin, D. W. H. * Eremophilane derivatives with a novel carbon skeleton  from Ligularia veitchiana. Tetrahedron 1997, 53, 6195–6208.

52. Chen, H.*; Tan, R. X.; Liu, Z. L.; Zhao, C. Y.; Sun, J. A clerodane diterpene with antibacterial activity from Ajuga lupulina. Acta Crystallogr. 1997, C53, 814–816.

51. Ma,  W. G.; Tan, R. X.; Fuzzati, N.; Li, Q. S.; Wolfender, J. L.;  Hostettmann K. ∗. Wahlenbergioside, a new phenylpropanoid glycoside from  Wahlenbergia marginata. Phytochemistry 1997, 45, 411–415.

50. Tang, H. Q.; Tan, R. X.* Glycosides from Gentiana scabra. Planta Med. 1997, 63, 388.

49. Tan, R. X.*; Kong, L. D. Secoiridoids from Gentiana siphonantha. Phytochemistry 1997, 46, 1035–1038.

48. Tan, R. X. *; Hu, J.; Kong, L. D.; Wolfender, J. L.; Hostettmann, K. Two new secoiridoid glycosides from Gentiana algida.  Planta Med. 1997, 63, 567–569.

47. Chen, H.; Jia, Z. J.; Tan, R. X. Two new oplopanol esters from Cremanthodium ellisii. Planta Med. 1997, 63, 245–247.

46. 郑维发,谭仁祥*,刘志礼. 牛尾蒿两变种精油的化学成分. 植物分类学报 1996, 34, 410–414.

45. Zhang, W. F.; Tan, R. X.*; Liu, Z. L. The composition of the essential oil of Artemisia giraldii. Journal of Plant Taxonomy 1996, 34, 410–414.

44. 郑维发,谭仁祥*,刘志礼, 杨际红,包艳雏. 八种蒿属植物石油醚提取物中萜类成分分析. 南京大学学报 1996, 32, 706–712.

43. Zheng, W. F. Tan, R. X.*, Z. L. Liu, J. H. Yang, Y. C. Bao. Comparative analysis of terpenoids from eight Artemisia species.Journal of Nanjing University 1996, 32, 706–712.

42. Tan, R. X., Wolfender, J. L.; Ma, W. G.; Zhang, L. X.; Hostettmann, K. *. Secoiridoids and antifungal aromatic acids from Gentiana algida. Phytochemistry 1996, 41, 111–116.

41. Zheng, W. F.; Tan, R. X.*; Liu, Z. L.; Yang, L. Two flavones from Artemisia giraldii and their antimicrobial activity. Planta Med. 1996, 62, 160–162.

40. Tan,  R. X.; Wolfender, J. L.; Zhang, L. X.; Ma, W. G.; Fuzzati, N.; Marston,  A.; Hostettmann, K. * Acyl secoiridoids and antifungal constituents  from Gentiana macrophylla. Phytochemistry 1996, 42, 1305–1313.

39. Tan,  R. X.*; Wei, H. X.; Cui, Y. X. NMR studies on the regio- and  stereo-selectivity of 1,3-dipolar cycloaddition of diazomethane to  alpha,beta-unsaturated spiroketals from Artemisia Species. Spectrosc. Lett. 1996, 29, 1035–1046.

38. Chen, H.∗; Tan, R. X.; Liu, Z. L.; Liu, J.; Chen, M. Q.; Lupulin D. Acta Crystallographica 1996, C52, 2229–2231.

37. Chen, H.; Tan, R. X.*; Liu, Z. L.; Zhang, Y. Antibacterial neoclerodane diterpenoids from Ajuga lupulina. J. Nat. Prod. 1996, 59, 668–670.

36. Zheng, W. F.; Tan, R. X.*; Yang, L.; Liu, Z. L. A new antimicrobial sesquiterpene lactone from Artemisia giraldii. Spectrosc. Lett. 1996, 29, 1589–1597.

35. Tan, R. X.*, Wang, W. Z.; Wu, S. X.; Yang, L. NMR Assignments and absolute configuration of kauranoids. Magn. Reson. Chem. 1995, 33, 749–754.

34. Tang, J.; Tan, R. X.*; Ding, X. L.; Tao, G. J.; Ding, S. D. Ding. IR and 13C NMR studies of anomeric mixtures of maltose. Spectrosc. Lett. 1995, 28, 261–273.

33. Tan, R. X.*, Wang, W. Z.; Yang, L.; Wei, J. H. A new eudesmenoic acid from Artemisia phaeolepsis. J. Nat. Prod. 1995, 58, 288–290.

32. Tan, R. X.; Jia, Z. J.*; Yan, Z. Q.; Deng, C. H. New eudesmane acids from Artemisia hedinii. Indian J.  Chem. 1995, 34B, 565–273.

31. Wang,  S. X.; Cui, Y. X.; Tan, R. X.∗; Luo, Q. H.; Shi, J. Q.; Wu, Q. J.  Synthesis, structure and 1H NMR spectra of cadmium complexes with  2,6-bis(benzimidazol-2'-yl)pyridine. Polyhedron 1994, 13, 1661–1668.

30. Wang, W. Z.; Tan, R. X.*; Yao, Y. M.; Wang, Q.; Jiang, F. X. Sesquiterpene lactones from Ajania fruticulosa. Phytochemistry 1994, 36, 1347–1349.

29. 严泽群,胡幼华,朱晓晴,谭仁祥. 甘青蒿化学成分研究. 中草药 1993, 24, 567–569 and 609.

28. Yan, Z. Q.; Hu, Y. H.; Zhu, X. Q.; Tan, R. X. Constituents of Artemisia tangutica. Chinese Traditional and Herbal Drugs 1993, 24, 567–569 and 609.

27. Tan, R. X.*, Hu, Y. H.; Liu, Z. L.; Pan, X. New kaurane diterpenoids from Aster tongolensis. J. Nat. Prod. 1993, 56, 1917–1922.

26. Zhao, Y.; Jia, Z. J*; Tan, R. X.; Yang, L.; New sesquiterpenes from the roots of Ligularia veitchiana. J. Nat. Prod. 1993, 56, 494–499.

25. Tan, R. X.; Jia, Z. J.* Guaianolides form Artemisia xerophytica. Phytochemistry 1992, 31, 191–193.

24. Jia, Z. J.*; Zhao, Y.; Tan, R. X.; Li, Y. Sesquiterpenes and other constituents from Ligularia veitchiana. Phytochemistry 1992, 31, 199–201.

23. Tan, R. X.; Jia, Z. J. Jia*. Eudesmanolides and other constituents from Artemisia argyi. Planta Med. 1992, 58, 370–372.

22. Zhao, Y.; Jia, J. Z.*; Tan, R. X.. Eremophilanolides from the roots of Ligularia veitchiana. Phytochemistry 1992, 31, 2785–2787.

21. Tan, R. X.; Jia, Z. J.*; Zhao, Y.; Feng, S. L. Sesquiterpenes and acetylenes from Artemisia feddei. Phytochemistry 1992, 31, 3135–3138.

20. Tan, R. X.; Jia, Z. J.* ; Zhao, Y. Sesquiterpenes from Artemisia rutifolia. Phytochemistry 1992, 31, 2534–2536.

19. Jia, Z. J.*; Zhao, Y.; Tan, R. X. New eremophilane type lactones from the roots of Ligularia veitchiana. Planta Med. 1992, 58, 365–367.

18. Tan, R. X.; Jia, Z. J.* ; Zhao, Y. Sesquiterpene lactones and other constituents from Artemisia feddei. Planta Med. 1992, 58, 459–460.

17. Tan, R. X.; Jia, Z. J* Revised structure of seco-tanapartholide B. Phytochemistry 1992, 31, 2158–2159.

16. Tan, R. X.; Jia, Z. J.* A new cycloartane triterpene from Artemisia argyi. Chinese Chem. Lett. 1992, 3, 117–118.

15. Tan, R. X.; Jia, Z. J.* ; Zhao, Y. C14 acetylenes from Artemisia feddei. Chinese Chem. Lett. 1992, 3, 283–284.

14. Zhao, Y.; Jia, Z. J.*; Tan, R. X.. New Eremophilanolides from the roots of Ligularia veitchiana. Chinese Chem. Lett. 1992, 3, 35–38.

13. Tan, R. X.; Jakupovic, J.; Bohlmann F.*; Jia, Z. J.; Huneck, S. Seaquiterpene lactones and other constituents from Artemisia xerophytica. Phytochemistry 1991, 30, 583–587.

12. Jakupovic, J. *; Tan, R. X.; Bohlmann, F. P.; Boldt, E.; Jia, Z. J. Sesquiterpene lactones from Artemisia ludoviciana. Phytochemistry 1991, 30, 1573–1577.

11. Jakupovic J.*; Tan, R. X.; Bohlmann, F. Jian, Z. J.; Huneck. S. Prenylated coumaric acid derivatives from Artemisia cf. dolosa. Phytochemistry 1991, 30, 1645–1648.

10. Jakupovic J.*; Tan, R. X.; Bohlmann, F. Z.; Jia, J. Z.; Huneck. S. S Sesquiterpene lactones from Artemisia rutifolia. Phytochemistry 1991, 30, 1714–1716.

9.  Jakupovic  J.*; Tan, R. X.; Bohlmann F.; Jia, Z. J.; Huneck, S. Seco- and  nor-sesquiterpene lactones with a new carbon skeleton from Artmeisia santolinifolia. Phytochemistry 1991, 30, 1941–1946.

8. Tan, R. X.; Jia, Z. J.*; Jakupovic, J.; Bohlmann, F.; Huneck. S. Sesquiterpene lactones from Artmeisia rutifolia. Phytochemistry 1991, 30, 3033–3035.

7. Jakupovic, J.*; Tan, R. X.; Bohlmann, F.; Jia, Z. J.; Huneck, S. Acetylenes and other constituents from Artmeisia dracunculus.Planta Med. 1991, 57, 450–453.

6. izuno, M.*; Tan, R. X.; Zhen, P; Min, Z. D.; Iinuma, M.; Tanaka, T. Two steroidal alkaloid glycosides from Veratrum taliense Phytochemistry 1990, 29, 359–361.

5. Tan, R. X.; Jakupovic, J.; Bohlmann, F.*; Jia, Z. J.; Schuster, A. Sesquiterpene lactones form Vladimiria souliei. Phytochemistry 1990, 29, 1209–1212.

4. Tan, R. X.; Jakupovic, J.*; Jia, Z. J. Aromatic constituents from Vladimiria souliei. Planta Med. 1990, 56, 475–477.

3. Jakupovic, J.*; Tan, R. X.; Bohlmann, F.; Jia, Z. J.; Huneck, S. Prenylated coumarates from Artemisia xanthochroa. Phytochemistry 1990, 29, 3683–3685.

2. *,谭仁祥,郑启泰,贺存恒. 大理藜芦碱B 的结构及其绝对构型的确定. 药学学报 1988, 23, 584-587.

1. Min, Z. D.; Tan, R. X.; Zheng, Q. T; He, C. H. The structure and absolute configuration of vertaline B. Acta Pharmaceutica Sinica 1988, 23, 584–587.


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